Steven R. Lane, MD, MPH, FAAFP, Clinical Informatics Director, Privacy & Interoperability, Sutter Health. Taking a clinical perspective, Dr. Steven Lane reviews the foundations and recent history of interoperability and health information exchange. He focuses on the emerging Carequality Framework and the increasing participation in and use of Carequality supported exchange since the first transactions in July, 2016. Dr. Lane also discusses Sutter Health’s experience with exchange since 2010 and new use cases that will be supported by the Carequality Framework over the coming years