Eric Alper, MD, SVP, Chief Quality Officer & Chief Clinical Informatics Officer, UMass Memorial Health Care, and Steve Meurer, PhD, MBA, MHS, Executive Principal, Data Science and Member Insights, Vizient Inc. Referencing the 2020 inpatient COVID data, trends and insights from the Vizient Clinical Database, which is a retrospective, comparative database of more than 800 hospitals, Drs. Alper and Meurer discuss the experience of managing the COVID pandemic in this large academic medical center with particular focus on explaining how COVID affected their resulting quality improvement efforts.