Jerry Osheroff, MD, AHRQ eRecommendation Project Director, Thomson Reuters; Robert E. Murphy, MD, Chief Medical Information Officer, Memorial Hermann Healthcare System; and Eboni Price-Haywood, MD, MPH, Co-Executive Director, Tulane Community Health Centers, discuss how an HIT project funded by the Agency for Healthcare Research and Quality (AHRQ) and supported by ONC staff can contribute to the process of developing CDS rules for performance improvement generally, and Meaningful Use in particular. This presentation provides the latest information about what the project is producing for clinical information system suppliers and CDS implementers and how to engage with the initiative. Presenters also speak about the insights of care delivery organizations that have pilot tested the eRecommendations format and about how these tools have been received to date by a broad range of stakeholders in the CDS value chain.