Rocco Orlando, MD, SVP and Chief Medical Officer, Hartford Healthcare, and John Johnston, CPA, MHA, VP, Optum Advisory Services. A five-hospital integrated delivery system in Connecticut, Hartford Healthcare has developed a strategy for integrating clinical and financial operations for high-reliability care that involves structuring teams at both the system and service line levels, interdisciplinary teams to implement and run with sustainable cost-cutting initiatives, and a governance model to identify and prioritize the most important opportunities to be more rigorous in reducing variation in quality and cost. Dr. Orlando and John will share their “lessons learned” in implementing this IT-enabled business and care model.