Voice technologies and ambient intelligence hold promise for improvements and efficiencies in clinical workflow. During the past few years vendors and services have emerged from both within and outside healthcare. The Scottsdale Institute convened 24 chief medical informatics officers (CMIOs) for a virtual roundtable on August 20, 2020, to discuss the current technologies and use cases of voice and speech technologies and their ability to help merge the historically siloed verticals of documentation, clinical documentation improvement (CDI), utilization management, case management, and billing coding, and enable these combined functions to be more clinically driven. The CMIO Roundtable Report captures that discussion.